Welcome to Topochemical Engineering & Biofabrication
Biofabrication is one of most promising sustainable technologies for production of materials, chemicals, pharmaceuticals, cosmetics and many other products for everyday life. Topochemical engineering is a new strategy to enhance biofabrication and to tackle current challenges for a better life quality.
Topochemical engineering
Topochemical engineering is a method of designing the fractionation (disassembly) and fabrication (assembly) of highly engineered functional materials using a combination of molecular and supramolecular techniques. Topochemical engineering is inspired on bioassembly observed in natural systems such trees and microorganisms.
Biofabrication
Biofabrication is a sustainable technology to produce biological polymers and molecules for applications as materials, chemicals, pharmaceuticals, cosmetics and other relevant products for everyday life. Biological polymers and molecules can be disassembled from biomass or produced in a bioreactor combined with synthetic biology.
Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs
Cellulose beads emerge as carriers for poorly water-soluble drugs due to their eco-friendly raw materials and favorable porous structure. However, drug dissolution may be limited by their poor swelling ability and the...
Biomimetic cellulose/collagen/silk fibroin as a highly interconnected 3D hybrid matrix for bone tissue engineering
The limitations of the existing graft materials in the bone reconstruction practice will be met by the porous polymeric scaffolds with osteoconductive property. In this study, microcrystalline cellulose (CEL) and collagen (COL) along with the silk fibroin (SF) protein were...
Lignin-based materials for emerging advanced applications
Lignin abundance worldwide is well-known, and the effort of academic research groups and industries to increase the use of this biopolymer in a wide variety of fields has not gone unnoticed. While lignin has...
Biopolymer Beads for Biomedical Applications
Polysaccharides are the class of biopolymers synthesized enzymatically, utilizing monosaccharide units as building blocks. The interesting properties of the polysaccharides such as biocompatibility, chemical functionalization, and processibility in the form of beads...
Biofabrication of Functional Pullulan by Aureobasidium pullulans under the Effect of Varying Mineral Salts and Sugar Stress Conditions
Pullulan is a linear exopolysaccharide, produced in the fermentation media of Aureobasidium pullulans, with a variety of applications in the food and pharmaceutical industries. Pullulan derivatives have growing potential for biomedical applications, but...
Advanced Fractionation of Kraft Lignin by Aqueous Hydrotropic Solutions
Lignin is an underutilized high-potential biopolymer that has been extensively studied over the past few decades. However, lignin still has drawbacks when compared with well-known petroleum-based equivalents, and the production of tailored...
Probiotics for oral health: do they deliver what they promise?
Probiotics have demonstrated oral health benefits by influencing the microbiome and the host. Although promising, their current use is potentially constrained by several restrictions. One such limiting factor lies in the prevailing...
Topochemical Design of Cellulose-Based Carriers for Immobilization of Endoxylanase
Xylooligosaccharides (XOSs) gained much attention for their use in food and animal feed, attributed to their prebiotic function. These short-chained carbohydrates can be enzymatically produced from xylan, one of the most prevalent...