Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs

Novel cationic cellulose beads for oral delivery of poorly water-soluble drugs

Cellulose beads emerge as carriers for poorly water-soluble drugs due to their eco-friendly raw materials and favorable porous structure. However, drug dissolution may be limited by their poor swelling ability and the...

Biomimetic cellulose/collagen/silk fibroin as a highly interconnected 3D hybrid matrix for bone tissue engineering

The limitations of the existing graft materials in the bone reconstruction practice will be met by the porous polymeric scaffolds with osteoconductive property. In this study, microcrystalline cellulose (CEL) and collagen (COL) along with the silk fibroin (SF) protein were...

Biopolymer Beads for Biomedical Applications

Polysaccharides are the class of biopolymers synthesized enzymatically, utilizing monosaccharide units as building blocks. The interesting properties of the polysaccharides such as biocompatibility, chemical functionalization, and processibility in the form of beads...

Probiotics for oral health: do they deliver what they promise?

Probiotics have demonstrated oral health benefits by influencing the microbiome and the host. Although promising, their current use is potentially constrained by several restrictions. One such limiting factor lies in the prevailing...

Topochemical Design of Cellulose-Based Carriers for Immobilization of Endoxylanase

Xylooligosaccharides (XOSs) gained much attention for their use in food and animal feed, attributed to their prebiotic function. These short-chained carbohydrates can be enzymatically produced from xylan, one of the most prevalent...

Porous soluble dialdehyde cellulose beads: A new carrier for the formulation of poorly water-soluble drugs

Cellulose beads are porous spherical particles with promising futures for drug delivery applications. In this study, novel dialdehyde cellulose (DAC) beads are developed by periodate oxidation of pristine cellulose for oral delivery of weakly...

Valorization of Aloe barbadensis Miller. (Aloe vera) Processing Waste

Aloe vera plant is known worldwide for its medicinal properties and application in gel-based products such as shampoo, soap, and sunscreen. However, the demand for these gel-based products has led to a surplus...

Structural characterization and protective effects of polysaccharide from Gracilaria lemaneiformis on LPS-induced injury in IEC-6 cells

This study was aimed to characterize Gracilaria lemaneiformis polysaccharides and evaluate their protective effects on Lipopolysaccharide-induced injury in IEC-6 cells. The G. lemaneiformis polysaccharide was degraded by UV/H2O2 treatment and purified to three fractions named GLP-1.0 M, GLP-1.4 M...

Preparation and properties of polyvinyl alcohol/N–succinyl chitosan/lincomycin composite antibacterial hydrogels for wound dressing

Hydrogels are three-dimensional polymeric networks capable of absorbing large amounts of water or biological fluids with the properties resembling natural living tissues. Herein, polyvinyl alcohol (PVA)/N–succinyl chitosan (NSCS)/lincomycin hydrogels for wound dressing...

TEMPO-oxidized cellulose beads as potential pH-responsive carriers for site-specific drug delivery in the gastrointestinal tract

The development of controlled drug delivery systems based on bio-renewable materials is an emerging strategy. In this work, a controlled drug delivery system based on mesoporous oxidized cellulose beads (OCBs) was successfully...