Topochemical Engineering & Bioinspired Fabrication

Biomimetic cellulose/collagen/silk fibroin as a highly interconnected 3D hybrid matrix for bone tissue engineering

The limitations of the existing graft materials in the bone reconstruction practice will be met by the porous polymeric scaffolds with osteoconductive property. In this study, microcrystalline cellulose (CEL) and collagen (COL) along with the silk fibroin (SF) protein were...

Structural characterization and protective effects of polysaccharide from Gracilaria lemaneiformis on LPS-induced injury in IEC-6 cells

This study was aimed to characterize Gracilaria lemaneiformis polysaccharides and evaluate their protective effects on Lipopolysaccharide-induced injury in IEC-6 cells. The G. lemaneiformis polysaccharide was degraded by UV/H2O2 treatment and purified to three fractions named GLP-1.0 M, GLP-1.4 M...

Preparation and properties of polyvinyl alcohol/N–succinyl chitosan/lincomycin composite antibacterial hydrogels for wound dressing

Hydrogels are three-dimensional polymeric networks capable of absorbing large amounts of water or biological fluids with the properties resembling natural living tissues. Herein, polyvinyl alcohol (PVA)/N–succinyl chitosan (NSCS)/lincomycin hydrogels for wound dressing...

In vitro and in vivo evaluation of poly-3-hydroxybutyric acid-sodium alginate as a core-shell nanofibrous matrix with arginine and bacitracin-nanoclay complex for dermal reconstruction of excision wound

The protective layer of the body, the skin is often prone to damage due to several factors like trauma, accidents, stress and hazardous exposure. This requires the skin to regenerate itself which...

Durable nanofibrous matrices augmented with hydrotalcite-like compounds for cutaneous regeneration of burn wounds

Electrospinning of Gelatin (G) and Poly-3-hydroxybutyric acid (P) incorporated with anionic drug (AgSD) loaded hydrotalcite (L) (L-AgSD) is carried out to fabricate a nanofibrous scaffold which would recreate the native extracellular matrix...

Fabrication of Biohybrid Polysaccharide-Protein Material for Wound-Healing Application

Tissue engineering is currently one the fastest growing engineering fields, requiring fabrication of advanced and multifunctional materials to be used as scaffolds or dressing for tissue regeneration. In this work, a bilayer...